Permanent, Direct His-Bundle Pacing

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Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation.

BACKGROUND Direct His-bundle pacing (DHBP) produces synchronous ventricular depolarization and improved cardiac function relative to apical pacing. Although it has been performed transiently in the electrophysiology laboratory and persistently in open-chested canines, permanent DHBP in humans has not been achieved. METHODS AND RESULTS A total of 18 patients aged 69+/-10 years who had a histor...

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Acute His Bundle Injury during Permanent His Bundle Pacing: Mechanistic Insights into Intra- Hisian Block

Permanent His bundle pacing (HBP) is a physiological alternative to right ventricular pacing. Acute injury to the His bundle can occur during permanent HBP in the form of transient or permanent bundle branch blocks. Observations of mechanical injury to the His bundle during HBP lead fixation and electrophysiological response to HBP provides additional mechanistic insights into the pathology of ...

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The potential and reality of permanent his bundle pacing.

Right ventricular apex pacing can have deleterious effects. Our aims were to investigate how many patients referred for permanent pacing were suitable candidates for permanent His bundle pacing, and to determine the proportion in whom such pacing was successful. All cases of suprahisian block and most cases of infrahisian block (71.4%) were corrected by temporary His bundle pacing. However, per...

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Step-wise Approach to Permanent His Bundle Pacing

There has been a recent upsurge of interest in permanent His bundle pacing, given increased understanding and appreciation of the role dyssynchronous ventricular activation plays in congestive heart failure and atrial fibrillation. Permanent His bundle pacing gives implanters the ability to avoid causing ventricular dyssynchrony in patients dependent on ventricular pacing, and can provide an al...

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Autopsy analysis of the implantation site of a permanent selective direct his bundle pacing lead.

To date, there has not been direct visualization of the anatomic location of direct His bundle pacing (DHBP) leads in the human heart. The absence of such data has contributed to disagreement about the location of DHBP leads with respect to the plane of the tricuspid valve.1,2 We present an autopsy study of a patient who had previously had a DHBP lead implanted, showing unequivocally that the l...

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ژورنال

عنوان ژورنال: Circulation

سال: 2000

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.101.8.869